Relative humidity below the 10th percentile was a risk factor for OHCA, independent of temperature, with borderline significance (OR = 1.16, 95%CI 0.96 1.38). The patients were on average 75.5 ± 16.2 years old and 55.8% of them were males.Įxposure to 90th and 10th percentile of temperature adjusted to humidity were positively associated with the OHCA with borderline significance (Odds Ratio (OR) =1.20, 95%CI 0.97 1.49 and OR 1.16, 95%CI 0.95 1.41, respectively). There were 12,401 OHCA cases (68.3% were pronounced dead-on-scene). In the case-crossover design, we compared ambient exposure within 72 h prior to the OHCA event with exposure prior to the four control times using conditional logistic regression in a lag-distributed non-linear model. We analyzed all adult cases of OHCA in Israel attended by EMS during 2016–2017. In this nationwide analysis, we aimed to assess the incidence of the OHCA events attended by emergency medical services (EMS), in relation to meteorological conditions: temperature, humidity, heat index and solar radiation. Climate change and global warming phenomenon have been found related to cardiovascular morbidity, however there is no agreement on their impact on OHCA occurrence. Out-of-hospital-cardiac arrest (OHCA) is frequently linked to environmental exposures. This effect is independent of temperature and humidity. Short-term exposure to high levels of pollution is adversely associated with OHCA.
The magnitude of the effect is modified by patients' demography. Short-term exposure to high levels of pollution is adversely associated with OHCA independently of meteorological conditions. Analysis stratified by regions suggested a spatial variability in pollution associated with OHCA. The adverse effect of PM10 was more evident during a weekend (OR = 2.36, 95%CI 0.88 6.28), as opposed to working days (OR = 0.81, 95%CI 0.45 1.44). An exposure to NO2 was independently associated with OHCA among males (OR = 1.39, 95%CI 0.96 2.01) and if occurred during the midweek (OR = 1.43, 95%CI 1.03 1.97). Patients experiencing OHCA were likely to be exposed to elevated levels of pollutants, specifically, nitrogen dioxide (NO2) and particulate matter of size ≤2.5 μm (PM2.5) several hours prior to an event, although both at borderline significance, i.e. All associations at study were investigated using a lag-distributed regression and adjusted to temperature and humidity. The air-pollution and meteorology data were retrieved from the 132 monitoring stations. In a case-crossover analysis, we analyzed all adult cases of OHCA in Israel during 2016–2017. We investigated the link between OHCA and a short-term exposure to particulate matter (PM) and other pollutants, within extreme climate conditions in Israel and high PM. Previous research suggested that an out-of-hospital cardiac arrest (OHCA) may be triggered by an exposure to ambient pollutants.
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